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Final exam لمادة موضوعات مختارة في علم الادوية
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عدد الاسءلة هي 63 سؤال
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Q1
Score: 0.5
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Q2
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A- fetal period
B- organogenesis
C- Blastogenesis
D- non the above
Q3
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Q4
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A- drugs
B- food additives
C- cosmetic
D- pesticide
E- all of the above
Q5
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Q6
Score: 0.5
Q7
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A- digoxin
B- NSAIDS
C- Atropine- like drugs
Q8
Score: 0.5
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Q9
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A- urinary retention
B- hyperglycemia
C- heart block
D- GI hemorrhage
Q10
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Q11
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A- spontaneous
B- route of exposure
C- species
D- sex of test animal formulation
Q12
Score: 0.5
A- lethal dose to assayed in the same population
B- dose required for sub- lethal toxicity
C- all the above
Q13
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A- Health
B- disease
C- organization
D- non the above
Q14
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A- pharmacodynamic drug- drug interaction
B- pharmacokinetic drug- drug interaction
C- pharmaceutic interaction
Q15
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Q16
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Q17
Score: 0.5
Q18
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A- factor including the vascular perfusion
B- By 6 weeks of age
C- such as penicillin
D- are reduced by 50% in premature
Q19
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A- treatment of pre- existing chronic disorder
B- always use drugs which have been widely used
C- over the counter
D- drugs for medical condition prior to confirmation of pregnancy
Q20
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Q21
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Q22
Score: 0.5
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Q23
Score: 0.5
A- sulfonamide
B- Aspirin
C- Mepiridine
D- Benzodiazepine
Q24
Score: 0.5
Q25
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A- poly pharmacy
B- multiple disease state
C- increase severity of illness
D- B+ C
E- all the above
Q26
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A- structural
B- spontaneous
C- antidotal
D- route of exposure
Q27
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A- chemical modification of known molecule
B- biotechnology and cloning
C- random screening for biological activity of large numbers of natural
D- all the above
Q28
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Q29
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Q30
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A- phase -1
B- phase- 2
Q31
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A- FDA
B- NMR
C- IND
Q32
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A- producing hypotension
B- producing hypoglycemia
C- producing hypertension
D- producing hyperglycemia
Q33
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A- Antibodies
B- vaccines
C- enzyme
D- DNA product
Q34
Score: 0.5
A- animal
B- human
C- in vivo
Q35
Score: 0.5
A- nasal hypoplasia
B- bone stippling on X- Ray
C- depressed bridge of nose
D- all the above
E- non the above
Q36
Score: 0.5
A- Clark's Rule
B- Youngs Rule
C- creatinine clearance
D- non the above
Q37
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Q38
Score: 0.5
Q39
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A- check chemical stability
B- determine major metabolite
C- optimize and scale up synthesis and purification
D- produce GMP batches are required for biological and clinical test
Q40
Score: 0.5
A- Arthritis
B-metabolism
C- peptic ulcer
D- stroke
Q41
Score: 0.5
A- transplant surgery
B- Apligraf
C- B cell
D- influenza
Q42
Score: 0.5
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Q43
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A- result in polar
B- water soluble
C- oxidase
D- conjugation
Q44
Score: 0.5
A- mental retardation
B- Mutagenesis
C- is seen in up to 25% of the fetuses with first - trimester exposure to coumarins
D- carcinogenesis
Q45
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A- drug action
B- cell
B- tissue
C- system
Q46
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A- pharmacodynamic
B- direct toxicity
C- genotoxicity
D- all the above
Q47
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Q48
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Q49
Score: 0.5
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Q50
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A- mental retardation
B- Hyperactivity
C- all the above
D- non of the above
Q51
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Q52
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A- Easily
B- with difficult
C- poorly
D- non of the above
Q53
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A- Aspirin
B- sulfonamide
C- chloramphenicol
D- Tetracycline
Q54
Score: 0.5
Q55
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A- gene
B- protein
C- cell
D- tissue
Q56
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A- Effect
B- Efficacy
C- Effectiveness
D- BENEFIT
Q57
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Q58
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A- 5- 10 years
B- 1 month
C- 15- 25 years
D- 9 month to 3 years
Q59
Score: 0.5
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Q60
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A- pregnancy
B- cough
C- diarrhea
D- heart
Q61
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Q62
Score: 0.5
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Q63
Score: 0.5
Q64
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A- chemical development
B- safety assessment
C- drug metabolism
D- all the above
Q65
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A- albumin
B- alpha-1 acid glycoproteins
C- T cell
Q66
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Q67
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A- category A
B- category B
C- category c
D- category D
E- category x
Q68
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A- dose
B- Age
C- systemic toxicity
D- Route
Q69
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A- strength of hypothesis
B- Availibility of target
C- market prediction
D- Toxicology
Q70
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A- pharmaceutic interaction
B- pharmacodynamic interaction
C- pharmacokinetic interaction
Q71
Score: 0.5
A- conducting a clinical trial
B- Analyzing the outcome of a clinical trial
C- Givrine permission so clinical trial
D- non the above
Q72
Score: 0.5
A- digoxin
B- TCAS
C- Atropine like drugs
Q73
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A- phase I
B- phase II
C- phaseI and II and III and IV
D- phase III
Q74
Score: 0.5
A- absorption
B- medication compliance
C- reduction in GI motility
D- Elimination
E- A+ D
F- all the above
Q75
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A- usually placebo controlled
B- phase IIa is exploratory and phase IIb is confirmatory
C- the opproxinate number of healthy subject is 50- 500
D- gives confirmation of clinical dose and regimen for efficacy
Q76
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Q77
Score: 0.5
A- Elderly people
B- Infant
C- they are the major consumer of drug
D- include polypharmacy
Q78
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Q79
Score: 0.5
A- In vivo
B- in human
C- in animal
D- in vitro
Q80
Score: 0.5
A- vaccination
B- blood transfusion
C- transplantation
D- drug therapy
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