Final exam لمادة الكيمياء الطبية ١
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Q1           Score:  1.11
 Four general classes of Glucuronides
 UDP
 Occur in many other tissue including kidney
 The main substrates for these enzymes are phenols
Q2           Score:  1.11
 Nitro , nitroso , hydroxylamine , amine
 Azo, hydrazo
Q3           Score:  1.11
 Less Alfa and beta activity
 Active isomer
 More Alfa and beta activity
Q4           Score:  1.11
 A- long preganglionic
 B- stimulates tear gland
 A + B
 Not all correct
Q5           Score:  1.11
 صح
 خطأ
Q6           Score:  1.11
 Muscarinic and nicotinic
 Alfa and beta
Q7           Score:  1.11
 Antimuscarinic drug
 Blood vessels
 Neuromuscular blockers
 Gangilonic blocker
Q8           Score:  1.11
 Product by single bond
 Product by triple bond
 Not of all correct
Q9           Score:  1.11
 Muscarinic
 Nicotinic
Q10           Score:  1.11
 Efferent
 Afferent
Q11           Score:  1.11
 صح
 خطأ
Q12           Score:  1.11
 Is catechol but not selective beta 2 agonist
 Is not catechol but selective beta 2 agonist
 Resorcinal
Q13           Score:  1.11
 Is synthesized and stored in the adrenal medulla
 Is the main adrenergic neurotransmitter
Q14           Score:  1.11
 Acetylcholine
 Nor epinephrine or epinephrine
Q15           Score:  1.11
 Acetyl transferase
 Methyl transferase
 UDP
 Sulfo transferase
Q16           Score:  1.11
 Methyl
 Alcohol
 Ketone
 Water
Q17           Score:  1.11
 Hydroxyl
 Aldo- keto
 Azo
 Carbonyl
Q18           Score:  1.11
 Short duration
 Long duration
Q19           Score:  1.11
 Phase 1 is functionalization : phase 2 is conjugation
 Phase 1 is conjugation : phase2 is functionalization
Q20           Score:  1.11
 2-4h
 3-6h
 10-15h
Q21           Score:  1.11
 Nicotine
 Muscarinic
 Carbachol
 Pilocarpine
Q22           Score:  1.11
 Carboxylic acid , aromatic
 Is most common in primate drug metabolism
 Are the most common amino acid conjugation in animal
Q23           Score:  1.11
 Uridine triphosphate
 Adenosine triphosphate
Q24           Score:  1.11
 Out of
 To , toward
Q25           Score:  1.11
 Antisecretory effect
 Mydriatic effect
 Antitremor and antirigidity effect
 Antispasmodic effect
Q26           Score:  1.11
 Cholinergic fiber
 Somatic motor fiber to skeletal muscle
 Noradrenaline , NA
Q27           Score:  1.11
 صح
 خطأ
Q28           Score:  1.11
 Secondary alcohol
 Primary alcohol
Q29           Score:  1.11
 Non selective Alfa and beta agonist
 Selective beta 2 agonist
 Beta 1 and beta 2 agonist
Q30           Score:  1.11
 Like NE
 Cholinergic agonist
 Nicotinic receptor
Q31           Score:  1.11
 N- oxide
 Carbonyl
 Acyl group
Q32           Score:  1.11
 Are hydrolyzed slowly in comparison to ester
 Are hydrolyzed highly in comparison to ester
Q33           Score:  1.11
 Glaucoma
 In tachycardia
 GI
Q34           Score:  1.11
 Replacement of the meta
 Insertion of ethyl
 All correct true
Q35           Score:  1.11
 Is analogous to o- and N- dealkylation
 Oxidative conversion of carbon - sulfur double bond
 Desulfuration
 Alcohol
Q36           Score:  1.11
 Used as drug in human
 Contain o= , o , N+ = acetylcholine
 Is hydrolases
 Amide
Q37           Score:  1.11
 Glucuronic acid
 Sulfate
 Glycine
Q38           Score:  1.11
 Carbonyl
 Azo
Q39           Score:  1.11
 صح
 خطأ
Q40           Score:  1.11
 Pilocarpine
 Carbamate
 Acetylcholine
Q41           Score:  1.11
 S=p product by s= o
 Desulfuration
 S= p product by s= N
Q42           Score:  1.11
 Central
 Peripheral
 All correct true
Q43           Score:  1.11
 Quaternary head with at least two methyl group
 Hydrocarbon taill attached to oxygen
 Degree of activity
 The distance between the methyl nitrogen
Q44           Score:  1.11
 In rate
 Reduction
Q45           Score:  1.11
 Cholinergic agonist
 Cholinergic antagonist
 Adrenergic agonist
 Adrenergic antagonist
Q46           Score:  1.11
 صح
 خطأ
Q47           Score:  1.11
 صح
 خطأ
Q48           Score:  1.11
 صح
 خطأ
Q49           Score:  1.11
 Benzodiazepine
 Many endogenous compound such steroid
 Alcohol
Q50           Score:  1.11
 Fight or flight
 Adrenergic
 Cholinergic
Q51           Score:  1.11
 Lactam is a nitrogen to nitrogen covalent bond : hydrazide is cyclic amide
 Lactam is cyclic amide : hydrazide is nitrogen to nitrogen covalent bond
Q52           Score:  1.11
 Only for its effects on the eye
 Peptic ulcers
 All correct true
Q53           Score:  1.11
 ( - No2)
 N= N
 C=o
 C=C
Q54           Score:  1.11
 Sulfate conjugation
 Fatty acid conjugation
 All correct true
Q55           Score:  1.11
 Salivary
 Sweat
 All correct true
Q56           Score:  1.11
 Still have the intrinsic activity
 Steric hindrance of ACH
 No hydrolysis
Q57           Score:  1.11
 It is the larger category
 Both agonist and antagonist
 Allosteric site
Q58           Score:  1.11
 صح
 خطأ
Q59           Score:  1.11
 Is an alkyl group.
 Is an antidote for acetaminophen poisoning
 Is hydroxyl and amino moieties
 All correct true
Q60           Score:  1.11
 Xanthine
 Nicotinamide adenine dinucleotide
 Aldehyde
Q61           Score:  1.11
 Disulfide
 Sulfoxide
Q62           Score:  1.11
 Alcohol dehydrogenase
 Xanthine oxidase
 All correct true
Q63           Score:  1.11
 Amino amide
 Amino alcohols
 All correct true
Q64           Score:  1.11
 Cholinergic fibers
 Adrenergic fiber
Q65           Score:  1.11
 صح
 خطأ
Q66           Score:  1.11
 Less potent
 More potent
Q67           Score:  1.11
 صح
 خطأ
Q68           Score:  1.11
 No ganglia
 Effector organ
 All correct true
Q69           Score:  1.11
 صح
 خطأ
Q70           Score:  1.11
 Alfa2- agonist
 Alfa 1 - agonist
 Beta blocker
Q71           Score:  1.11
 The onium group
 The ester group
 The choline moiety
Q72           Score:  1.11
 Carboxylic acid + alcohol
 Alcohol + acid
 Not all correct
Q73           Score:  1.11
 Drug targeting
 Improving chemical stability
 All correct true
Q74           Score:  1.11
 Is a competitive blocking agent of the parasympathetic nervous system
 Effictive in preventing motion sickness
 Adrenergic agonist
Q75           Score:  1.11
 Extended conformation of ACH
 Folded conformation of ACH
 All correct true
Q76           Score:  1.11
 By GTP and G proteins
 Extracellular domain
 Ligand - gated ion channel receptor
Q77           Score:  1.11
 Uses NAD+ as cofactors
 The enzyme metabolizes alcohol containing drug ex : caffeine
 Enzyme is localized in soluble fraction of liver
Q78           Score:  1.11
 صح
 خطأ
Q79           Score:  1.11
 This is one of the most common detoxification reaction of a phase 1 type to occur in the body
 Alcohol
 Ketone
Q80           Score:  1.11
 Smooth
 Liver
 Alcohol
Q81           Score:  1.11
 Cholinergic agonist
 Cholinergic antagonist
 Adrenergic agonist
 Adrenergic antagonist
Q82           Score:  1.11
 Organophosphates
 Carbamates
Q83           Score:  1.11
 صح
 خطأ
Q84           Score:  1.11
 Is an aminoamide
 Use of eye
 Non all correct
Q85           Score:  1.11
 Alfa 2
 Beta 2 -selective
 Alfa -agonist
Q86           Score:  1.11
 O- de- ethylation
 O- demethylation
Q87           Score:  1.11
 Acetylcholine
 Alfa and beta
 Muscarinic and nicotinic
Q88           Score:  1.11
 صح
 خطأ
Q89           Score:  1.11
 Hypotension
 In the eye
 All correct true
Q90           Score:  1.11
 صح
 خطأ


   



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